In the liver, it is processed by FMOs, particularly FMO3, to create TMAO
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Differentials to be considered Addison Disease Blue Nevi Ephelides (Freckles) Kaposi Sarcoma Oral Nevi Other Problems to be Considered: Amalgam tattoo Graphite tattoo Oral melanotic macule Peutz-Jeghers syndrome Physiologic pigmentation The amalgam tattoo is a frequent finding in persons who have had amalgam restorations (ie, fillings)
Effect: a pulse of natural GH, then a rise in IGF-1
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It is a tripeptide with a gamma Peptide linkage between the carboxyl group of the glutamate side chain and cysteine