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ICH Q2(R2) explains that analytical procedures may be used for identity, purity, impurity, assay, and related measurements, which is why the method field matters [19]

In obesity, hypertrophic expansion of adipocytes leads to hypoxia, oxidative stress, and the release of pro-inflammatory adipokines, thereby promoting insulin resistance and ectopic lipid deposition [31]

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Sahoo BM, Banik BK, Borah P, Jain A