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Genetic polymorphisms in NMDAR subunits, such as NR1 and NR2B, influence individual sensitivity to the therapeutic and toxic effects of ketamine (Smith-Apeldoorn et al., 2022)

Wegovy use for licensed indications (obesity management) is a legitimate medical treatment and should generally not impact employment decisions, though employers may consider fitness to work in safety-critical roles

In the Phase 2 trial, up to half of retatrutide participants in the higher-dose groups reported these side effects

Melatonin users have called for more affordable and accessible alternatives of the sleep hormone

Women of childbearing age must use reliable contraception while on GLP-1 therapy, and treatment should be discontinued at least 2 months before attempting pregnancy to ensure complete drug clearance

Macks C, Gwak SJ, Lynn M, Lee JS