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Thats usually a conversation people have with their doctors, who know a lot about these medications and how they work. Even though it may seem like everyone on social media is talking about microdosing Ozempic, you shouldnt do it or adjust your dosage without consulting your healthcare provider first
Current guidelines do not recommend combination therapy with GLP-1 RAs and DPP-4 inhibitors, and the ADA/EASD consensus report specifically recommends discontinuation of DPP-4 inhibitors when initiating GLP-1 RA therapy
J Craniofac Surg 12:349354 Rickart AJ, Drummond-Hay V, Suchak A, Sadiq Z, Sebire NJ, Slater O, Mills C (2019) Melanotic neuroectodermal tumour of infancy: refining the surgical approach
Although the study primarily reports clinical outcomes, changes in specific biomarkers indirectly suggest potential mechanisms of action of GLP-1RAs