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Rectal mesalazine should be used for UC owing to higher efficacy[24,35]
Since your body naturally does not make vitamin B12 on its own, you will have to take it from another source like animal-based foods, pill supplements, or injections
Maintain aseptic handling to preserve compound integrity
Safety assessments in various animal models revealed no significant toxicity or adverse impact on physiological markers (Fawcett 2010)
Note that our body is not very efficient at absorbing vitamin B12 from supplements, so it's better to stay on the safe side by aiming to consume well over the minimum recommended amount, rather than taking a little less or sticking to the RDI
Strict adherence to the 28-day discard window, combined with proper refrigeration and aseptic technique, is the only reliable way to manage bac water shelf life safely
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