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The peptide was originally developed to treat growth hormone deficiencies and later gained attention in wellness and performance medicine for its ability to enhance GH release and improve IGF 1 levels
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In those experiments, pretreatment with the peptide enhanced subsequent responses to growth hormone stimulation, including increased cell viability, elevated proliferating cell nuclear antigen (PCNA) expression, and greater JAK2 phosphorylation activity [5]
Robins et al., 2005
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