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Linnebjerg H, Kothare PA, Park S, Mace K, Reddy S, Mitchell M, et al
For the primary composite outcome and secondary hierarchical outcomes, the threshold for two-sided statistical significance was set to 0.0322 (one-sided level 0.00161) using Lan-DeMets alpha spending function, which allows to adjust significance levels as data were reviewed for the interim analysis, reducing the chance of false positive results
Impact of lithium on the immune system: An investigation of T-cell subpopulations and cytokine responses in rats
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By six months, the participants had lost 12.7% of their body weight on average
