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Its effects are dose-dependent: low concentrations (520 M) enhance antioxidant capacity (e.g., 20 M curcumin increased SOD activity by 47% in RAW264.7 cells) (Lin et al., 2019)
PMID: 25249298, PMCID: PMC4323804, DOI: 10.1161/jaha.114.001197
Yeo and colleagues explained that with rising obesity in the U.S., the increasing prevalence of GLP-1 receptor agonists prescribed for obesity may contribute to drug shortages. Further, drug shortages may exacerbate the existing nationwide racial and ethnic disparities in GLP-1 receptor agonist prescriptions, they wrote, adding that the results suggest a call for strategies to address the growing demand and ensure equitable access to the drugs.
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