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In an online survey of 153 adults with obesity, most of whom were white and women, those who took semaglutide or tirzepatide reported drinking significantly less than peers not on the medications

Retatrutide leverages this same dual pathway while adding something tirzepatide cannot

These drugs also play a role in regulating metabolism

For Wegovy, there are also warnings for a heart rate increase and suicidal behaviour or ideation

All of these factors contribute to a higher risk of cardiovascular disease, which is the leading cause of death for women

Canadas certificate of supplementary protection register lists semaglutide with patent 2601784, a March 20, 2026 patent expiry date and a CSP term that would have extended to March 20, 2028