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In rodent studies, GLP-1 medications caused thyroid C-cell tumors, including medullary thyroid carcinoma (MTC)

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( I ) MTT assay for cell survival rate at 24 h, * vs

Group 1 did not have modified sperm patterns during treatment

Several factors influence the patients level of adherence and can be distinguished as social and economic factors, patient-related factors (health beliefs, health literacy), therapy-related factors (complexity of the treatment, adverse events), presence of comorbidities (neurological/psychiatric or of different origins), and factors related to the healthcare system (doctor-patient relationship, difficulty in obtaining follow-up visits)

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