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3 Newer medication classes, such as glucagon-like peptide-1 receptor agonists (GLP-1 RAs) and sodium-glucose co-transporter 2 (SGLT-2) inhibitors, target some of the more recently identified defects described in the ominous octet. Agents from these medication classes are increasingly recommended in clinical practice guidelines and recommendations

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A mobile phase of 2.5 mM H 2 SO 4 at a 0.5 mL/min flow rate was used, and the column was operated at 55 C [41]

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FAs and PUFAs disrupt vital metabolic functions linked to the bacterial cell membrane, including the electron transport chain and oxidative phosphorylation