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Ten deaths (1%) on tirzepatide and 12 (1%) on glargine were adjudicated as undetermined, and thus considered cardiovascular deaths for MACE determination
The evidence bases for the two peptides differ in depth and maturity, and it is important to distinguish preclinical (animal) work from human clinical data
2023 Aug 10;389(6):514-526
Montrose-Rafizadeh et al., 1994
7 Other nucleo-cytosolic acetyl-CoA generating pathways are intact in CCNE1-driven cells, and acetate does not increase histone acetylation in CCNE1-driven cells
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