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Comparison with Mendelian randomization analyses of body mass index and T2D genetic liability Mendelian randomization analysis was performed to investigate the effect of genetic liability to lower body mass index (BMI) and lower T2D risk on the circulating proteome, using genetic association estimates for circulating proteins from the deCODE cohort

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*Significance level 5%

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At the same time, Lactobacillus rhamnosus derived extracellular Vesicles can regulate the process of adipocyte metabolism, inhibit the excessive release of inflammatory factors, reduce the chronic inflammatory reaction of adipose tissue, and improve dyslipidemia (Tong et al., 2021)

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