The patients who maintained the most weight loss shared common traits: they had made significant dietary changes , increased physical activity, and often used a structured tapering approach rather than stopping abruptly
There are also more serious risks to consider, such as pancreatitis, gallbladder problems, kidney issues, thyroid tumors, and severe gastrointestinal conditions
If you are feeling stressed , anxious, or depressed (or maybe a bit of all three), getting help can make you feel better and less hungry
People interested in detoxification support , whether they're exposed to environmental toxins or simply want to support their liver's natural cleansing processes, often find great benefit from these treatments
The Numbers That Matter: In the landmark SURMOUNT-5 trial published in the New England Journal of Medicine in May 2025, participants taking tirzepatide lost an average of 20.2% of their body weight over 72 weeks, compared to 13.7% with semaglutide
"Long-term data beyond two to three years are still accumulating," Srivastava says