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Therefore, practitioners must recognize early non-responsedefined as less than 2% weight loss within four weeksas a reliable predictor warranting prompt medication consideration

Eligibility is determined by a licensed healthcare provider based on individual goals, health history, and overall suitability

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Due to their safety profile, probiotics are a good option for pregnant or lactating women or patients with long term usage of antibiotics

Competing interests The authors declare that they have no competing interests and all authors agree to contribute to this journal

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