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Glucose-dependent insulinotropic polypeptide (GIP), another nutrient-stimulated hormone, regulates energy balance through cell-surface receptor signaling in the brain and adipose tissue

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2016 Sustained weight loss of 15.2% at week 104 with 2.4mg weekly

Beyond its effects on glucose regulation, Ozempic slows gastric emptying, which means food remains in the stomach for longer periods