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Of note, the tandem -grasp fold that forms the periplasmic domain of Wza can also be found in the group 4 polysaccharide capsule protein GfcC 41

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For instance, a study published in the New England Journal of Medicine reported that Liraglutide, a GLP-1 receptor agonist, led to substantial weight loss and improvements in glycaemic control in obese patients with type 2 diabetes

however, semaglutide is known to show higher GI side effects compared to others 12

Phase 1 and Phase 2 testing of full-length T4 found no dose-limiting toxicities, with adverse events mild and transient

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