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For specific goals like fat loss or performance enhancement, dosing may vary, and it's important to consider factors like body weight and activity level

Starting at a low dose and escalating slowly is one of the most effective ways to improve tolerability. Diarrhea Diarrhea is more common during dose escalation periods when the body is adapting to a higher amount of medication

Endothelial cell expression of haemoglobin regulates nitric oxide signalling

Lancet Diabetes Endocrinol 2025

However, during clinical trials, researchers found that it also had a significant effect on weight loss

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