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However, it is not recommended for use in newborns or premature infants, as neonates lack the metabolic capacity to process benzyl alcohol safely a contraindication explicitly noted in FDA guidance on benzyl alcohol toxicity in neonates

All causes for an inadequate response should be addressed before additional agents are added to a patients antihypertensive regimen (Box 12-3)

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In neuroprotection studies, DSIP has also shown potential benefits in reducing oxidative stress and improving mitochondrial function

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