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Procedure: Intramuscular (IM) Injection, self-administered in frontal thigh area
The rationale is that the membrane fusion proteins on the infectious virus necessary to merge the viral with the host cell membrane are in prefusion conformation, exposing epitopes unique to this structure that can be targeted by neutralizing antibodies to prevent infection before the virus enters the cell
The product monograph for Ozempic reports that the lowest dose produces a GLP-1 level of 65 nanograms per millilitre (one nanogram = 1,000 picograms)
It also provides the clinical foundation for asking whether adding glucagon receptor activation can further increase efficacy
This compound is made from the amino acids lysine and methionine
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