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Regard JB, Zhong Z, Williams BO, Yang Y (2012) Wnt signaling in bone development and disease: making stronger bone with Wnts

Excess weight can lead to insulin resistance, a condition where the bodys cells dont respond well to insulin, causing the pancreas to produce more to help glucose enter the cells

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Payers dont consider this sustainable, as it crowds out their ability to cover drugs in other therapeutic categories

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