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Am J Kidney Dis 59(4):513522

While PMS includes mood swings, irritability, and fatigue, PMDD presents a much more severe set of symptoms, including: Severe depression and irritability Anxiety and mood swings Increased cravings and hunger Fatigue and sleep disturbances Unlike PMS, PMDD significantly impacts daily functioning, making it hard for women to perform regular tasks

Shi S, Lei S, Tang C, Wang K, Xia Z (2019) Melatonin attenuates acute kidney ischemia/reperfusion injury in diabetic rats by activation of the SIRT1/Nrf2/HO-1 signaling pathway

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