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Olivera JA, Ries S, Jindani R, Rodriguez E, Azap L, Eisenberg MA, Clarke C, Bostock IC, Alimi YR, Raz DJ, Antonoff MB
- The Guardian
2025 Nov 20;17:100233
[32] Puskarich MA, Kline JA, Krabill V, Claremont H, Jones AE
In this narrative review, we summarize the rationale, receptor biology, pharmacological mechanisms, inflammatory signaling hypotheses, clinical evidence, safety concerns, and implementation challenges related to GLP-1RA use in obesity-related KOA
These findings hint at a much broader therapeutic future for these medications, potentially offering relief for millions beyond the diabetic population
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