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The companies will initially commence four development programs for potential small-molecule therapies directed to one or more select GPCR targets, including GLP-1, GIP, and glucagon receptors
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Blood glucose levels are tightly regulated within a very narrow range in individuals with normal glucose tolerance, which is maintained by the coordinated action of islet and incretin hormones, as well as neural and humoral factors from different tissues and organs
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The fact that some patients do not show venous sinus stenosis suggests that venous sinus stenosis may be the result of a pathological process of IIH
