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In a study of 10 healthy male volunteers, omeprazole, in doses of 20 mg40 mg per day, caused a significant decrease in the oral absorption of methylcobalamin, vitamin B12
In a 26-week rat oral toxicity study, AOD-9604 produced dose-dependent changes in serum osteocalcin (a bone-turnover marker) at week 13, with the direction reversing by week 26
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