Werner JA, Davies R, Wahlstrom J, Dahal UP, Jiang M, Stauber J, et al
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Schssler, P., Yassouridis, A., Uhr, M., Kluge, M., Weikel, J., Holsboer, F., & Steiger, A
Both medications target the same hormonal pathways, and combining them significantly increases the risk of severe gastrointestinal side effects and other medical complications without providing additional benefits
Topical or patch GLP-1 forms are not FDA-approved
Retatrutide is a 26-amino acid triple agonist that adds glucagon receptor activation to those two pathways