Kenchaiah S, Evans JC, Levy D et al (2002) Obesity and the risk of heart failure
Interestingly, higher incidence of diabetic retinopathy (DR) complications was noted in patients taking semaglutide (3.0%) compared to placebo (1.5%) in clinical trials, with greater risk in those with a history of DR [32]
Anaphylaxis is a severe reaction to a trigger, such as an allergy, and is potentially life threatening
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GLP-1 also promotes neurogenesis by stimulating neurotrophic factors as GDNF, VEGF, and BDNF and reduces inflammation by decreasing TNF-a, IL-6, IL-10, and microglial activation (Erbil et al., In addition to its role in neuroprotection, current evidence showed that GLP-1 affects reward pathways
GLP-1s can result in nutrient gaps and decreased muscle mass due to decreased food intake and inadequate protein consumption due to decreased appetite