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Discussion In a population of patients with type 2 diabetes who had no prior diagnosis of eye diseases, this cohort study found that semaglutide or tirzepatide compared with other antidiabetic medications was associated with a differential risk of optic nerve and visual pathways, including increased risk of NAION and other optic nerve disorders, but not optic neuritis, papilledema, optic atrophy, or optic disc orders

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coli by 38% (p = .004), with improvements in superoxide production and neutrophil migration

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Funding This research was funded by the Deputyship for Research & Innovation, Ministry of Education, in Saudi Arabia, which has supported this research work with the project number (UB-14-1442)