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Circulation and energy metabolism of the brain
PMID 29543316
These therapeutic concentrations range from 5 to 20 mg/ml
While a direct link between excess iron and optic neuropathies is not established, iron's ability to produce highly reactive ROS may play a role in its pathogenesis
Conclusion In vitro models of ECD allow the study of cellular and molecular mechanisms of disease and provide important research platforms for screening potential therapeutic agents
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