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Afamelanotide is FDA-approved for EPP at 16 mg subcutaneous implant every 60 days roughly 2 mg/day of continuous release (Langendonk et al., 2015)

This is something that I teach even in our introductory courses for undergrads, she said

In the SURMOUNT-1 trial, the highest dose achieved approximately 22.5% weight loss over 72 weeks

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