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For any transdermal medication system, the prescribed wear time is determined by the drug's pharmacokinetic profile and the patch's delivery technology

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Hepatology 2000

FX exerts its antioxidant impact through increasing antioxidant enzyme activities (catalase, gluthathione peroxidase (GSH-Px)) and total antioxidant capacity (TAC) of plasma, as well as enhancing mRNA expression of nuclear erythroid factor like 2 (Nrf2), which increases the synthesis of antioxidant proteins such as heme oxygenase-1 (HO-1) and NAD(P)H quinone oxidoreductase 1 (NQO1) (Liu et al., 2011