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1,2 However, the overproduction of ROS can induce cytotoxicity and lead to DNA damage and cell apoptosis

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Initial high-throughput compound screening and further medicinal chemistry-based optimization developed two novel series of phenylurea-based compounds inhibiting GOT1 enzymatic activity with potencies in the low micromolar IC 50 range 155

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Educational background: Semaglutide as a molecule was originally developed for type 2 diabetes by Novo Nordisk and is sold under the brand names Ozempic (for diabetes) and Wegovy (for chronic weight management, introduced for weight management in 2021)

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Panosyan, E

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Multidisciplinary care optimizes outcomes regardless of the chosen therapeutic approach

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