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Alternatively, UMP can be converted to a deoxy form (dUDP) to be used as substrate for the synthesis of thymidine
Increases in p53 expression induce CTGF synthesis by mouse and human hepatocytes and result in liver fibrosis in mice
This mechanism does not broadly stimulate cell death but instead targets a survival dependency characteristic of senescent cells
10.1038/297072a0 12 BlackC
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