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After baseline GSH measurement, 200 mg (in)GSH was self-administered inside the scanner without repositioning, then serial GSH levels were obtained over ~1 h

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This notion is supported by a recent pre-clinical study that showed that the downregulation of hepatic SHMT2 in mice led to changes in hepatic glycine and serine content, which reduced hepatic methylation potential and modulated hepatic fat synthesis, fibrosis, and inflammation 36

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The Certificate of Analysis includes both HPLC chromatogram and ESI-MS identity confirmation, available upon request via [email protected]

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