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While these immune mechanisms are essential for mycobacterial control, they lead to exudative meningitis, endovasculitis, infarction, hydrocephalus, and irreversible neuronal damage
Among currently available agents, GLP-1 RAs - and tirzepatide in particular, based on the SURMOUNT-1 subgroup analysis - have the most substantial weight-loss evidence in this population, with efficacy appearing comparable to that observed in common obesity
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Cornier M-A et al, The metabolic syndrome
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