A 2025 systematic review of the musculoskeletal literature found that BPC-157 improved outcomes in muscle, tendon, ligament, and bone injury models, while noting that the evidence comes largely from animal studies [1]
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Drug Delivery And Translational Research
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A 2019 review in Cell and Tissue Research examined BPC-157 for musculoskeletal soft-tissue healing and concluded that while studies consistently reported positive healing effects, the majority of studies have been performed on small rodent models and the efficacy of BPC 157 is yet to be confirmed in humans. It also noted that only a handful of research groups have studied the peptide in depth