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In DURATION-8, 695 patients were randomized to receive exenatide QW plus dapagliflozin (n = 231), exenatide QW (n = 231), or dapagliflozin (n = 233)
Of note, there were only 45 patients in this trial and there was no placebo arm
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They share common GI side effects, such as nausea, diarrhea, and vomiting
When HbA1c is considered unreliable for example, due to B12 deficiency or anaemia UK and WHO guidance recommends using a fasting plasma glucose test or a 75 g oral glucose tolerance test (OGTT) for diabetes diagnosis or assessment
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