Long R3 IGF-1 has a lower binding affinity for binding proteins such as IGFBP-3, which means it can circulate freely in the bloodstream and exert its anabolic effects on muscle cells without being inhibited by these binding proteins
Liraglutide (Saxenda) represents another licensed option for weight management in the UK
When starting Mounjaro, it is suggested to reduce the dose of concomitantly administered insulin or insulin secretagogues (e.g., sulfonylureas) to prevent hypoglycemia
The new 5-HT hypothesis of depression: cell-mediated immune activation induces indoleamine 2,3-dioxygenase, which leads to lower plasma tryptophan and an increased synthesis of detrimental tryptophan catabolites (TRYCATs), both of which contribute to the onset of depression
These symptoms typically don't require treatment with fast-acting carbohydrates unless blood glucose is actually below 70 mg/dL
Supporting your gut bacteria through fermented foods and probiotic supplements creates an environment that favors GLP-1 production via short-chain fatty acids