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This suggests a potential link between 15(S)-HETE and insulin resistance, where it may interfere with insulin signaling mediated by the PI3K/Akt pathway, thus acting as a bridge between metabolic disorders and reproductive dysfunction
However, all observed effects derive from animal models and in vitro research systems
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Research like the 2025 Kuceki study shows that combining copper peptides with microneedling further enhances delivery to the target cells
doi:10.1007/s00210-023-02452-2
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