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Hydrocarbon stapling also enhances the pharmacological performance of peptide drugs by dramatically improving target affinity, resistance to proteolysis, cell permeability, and in vivo pharmacokinetics 33,34
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155,156,157 Uricase, an enzyme responsible for converting UA into allantoin and urea, is found in various bacterial species including Bacillus pasteurii, Proteus mirabilis, and E
Nguyen, D
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