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This suggests that the antiatherosclerotic effects of short-term GLP-1 may not play a central role in atherosclerosis
Specifically, GLP-1 activated the PI3K/Akt cascade through phosphorylation, enhancing CREB activation and promoting the expression of BDNF and other neurotrophic factors
Staying at very low doses long term likely reduces benefit
In one study, people lost up to 21% of their body weight at 88 weeks
A BMI 30 is associated with increased health risk, but individual clinical evaluation by a physician determines the diagnosis
Medicines to help with nausea, such as ondansetron, or treatments for constipation or diarrhea may be used when needed
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