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NICE guidance requires at least 5% weight loss after 6 months at maintenance dose for treatment continuation, with maximum recommended duration of 2 years
medRxiv (Cold Spring Harbor Laboratory)
Many people increase doses prematurely, never giving any single dose enough time to reach its full potential
OTC options like antacids, H2 blockers, or PPIs may also provide short-term relief
Researchers are exploring how this effect may contribute to changes in metabolic rate and overall energy balance within controlled research settings
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