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MOTS-c is a mitochondrial-derived peptide that activates AMPK, the same metabolic switch exercise and fasting flip, improving insulin sensitivity, mitochondrial function, and metabolic flexibility

What you consume around the time of taking this supplement can either powerfully enhance its effects or entirely counteract them

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Kumar C, Igbaria A, D'autreaux B, Planson AG, Junot C, et al