Female participants (56% of the cohort) achieved an average of 25.3% weight loss at week 48
According to Eli Lilly's full year 2025 results, Mounjaro and Zepbound together posted combined sales of $36.5 billion, accounting for 56% of the company's total revenues of $65.2 billion, making tirzepatide the world's best-selling drug in 2025
GLP-1 drugs are effective because they delay the stomach from emptying, creating a feeling of fullness, thereby having an increased effect on weight loss
Food and Drug Administration (FDA) has approved semaglutide, a glucagon-like peptide receptor agonist (GLP-1RA), to treat type 2 diabetes mellitus (T2DM) and obesity
This is particularly evident in specific cardiovascular conditions such as heart failure with preserved ejection fraction (HFpEF), for which effective treatments are scarce
Ready to see what's possible