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TM3 cells were harvested after treatment, stained with Annexin V-FITC and PI reagent, and incubated in the dark for 15 minutes

While early results are promising, many studies are either small, in-vitro, or not rigorously controlled

A 2013 study reaches similar conclusions

[2] Activates collateral pathways to bypass vessel occlusions in ischemia-reperfusion scenarios (Pringle maneuver, Budd-Chiari syndrome)

The authors noted that this proliferation-inhibiting effect could have potential utility in anti-tumor applications, though further studies are needed to confirm its relevance in oncology contexts [43]

Presented for research literature review only Harkey MA et al