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Webb C, Bedwell C, Guth A, Avery P, Dow S
The clinical presentation can vary widely depending on the type of mutation affecting SLC22A5 and the phenotypic manifestation of the mutation, i.e., age of onset, organ involvement, and severity of symptoms at the time of diagnosis (34)
Handle the whole vial according to its most fragile component
For others, results appear more gradually
The main mechanism of action of antidepressants is to enhance the concentration of cAMP, thereby inducing alterations in the cAMP signaling cascade and its downstream target, pCREB BDNF (Gao et al., 2022)
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