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A chronic degenerative condition has more damaged tissue to clear and remodel before functional improvement occurs

Here is where intellectual honesty has to cut in both directions, because the point of this article is evidence, not advertising

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Seek medical attention promptly if you experience symptoms that could suggest serious underlying conditions, including: Unexplained weight loss or persistent fatigue Jaundice (yellowing of skin or eyes), abdominal pain, or swelling Easy bruising or bleeding , or unusual skin rashes Night sweats , fever, or enlarged lymph nodes Reduced urine output , significant swelling in legs or ankles Persistent itching without obvious skin cause These symptoms may indicate liver disease, haematological disorders, or renal impairmentconditions that can elevate B12 and require specialist assessment

The results showed that the T4 eye drops improved ocular discomfort and increased tear volume compared to placebo.[ref] Bacterial eye infection: Using T4 along with an antibiotic improved the healing of infections in the cornea.[ref] Microneedle patch: An interesting clinical trial used TB4 in extracellular vesicles along with stem cells for healing diabetic wounds

Alcohol misuse reduces B12 stores