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Setting up pharmaceutical ingredient supply chains that adhere to the complex regulations on manufacturing and quality could take monthsor perhaps longer if the Administration were to require them be sourced in the United States rather than China

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Animal studies have confirmed that even tiny paramagnetic iron oxide nanoparticles persist in the liver and spleen for several months, making it challenging to use repeated doses of nanoparticles in procedures such as hyperthermia or MRI, and raising concerns about inflammatory responses [202]

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