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In physiological conditions, oxidized GSH can be recycled intracellularly by GSH reductase (GR) using NADPH as a reducing power

There are several potential reasons for the reduced magnitude of effects on primary endpoints related to cognitive decline

SGLT2 inhibitors is the ability of these medications to enhance the activity of incretin hormones (that is, GLP-1 and glucose-dependent insulinotropic polypeptide), delaying gastric emptying and reducing gastrointestinal motility, Alkabbani and colleagues explained

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