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[22] Dose adjustment strategies may be necessary for patients with persistent symptoms
Treat your dose like a thermostat, not a gas pedal
Just enough to have something in the stomach
Hypoglycemia It is well known that GH, together with glucagon, cortisol, and epinephrine, display counterregulatory actions protecting from hypoglycemia, and that its excess may have a diabetogenic role as seen in subjects suffering from acromegaly ( In a double-blind RCT in T2D patients, a single dose of the GLP-1 analogue albiglutide did not impair the -cell response or GH secretion when blood glucose was clamped in the hypoglycemic range ( 2460 h), FFAs represent the key fuel of whole-body energy homeostasis
& Pascual, V
10.1136/heartjnl-2016-309781 32
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